I have been asked to resign at my first 121 regional. I made it through ground training OK, but the problem was in IOE. At the end of my first trip, my check airmen recommended more time. I was flying the E-175 struggling mostly with the automation, especially descending to the FAF after the STAR. My second attempt of IOE was split between two very different check airmen which was quite a disadvantage. On my last flight, I was still making small mistakes, and I wasn't recommended for a line check. I expected another final chance from management, but ultimately was asked to resign. I guess I am seen as a liability at this point. That's the short version, and now I'm trying to put that behind me. My question is: how do you recommend discussing this on my next interview? It's not considered a fail, just an incomplete. How can I still have a successful interview without being a "liability" to the next company? I'm sending updated apps to other regionals, hoping that going through training a second time will be smoother. I am also posting this to advise everyone to pass IOE by the second attempt! I know most people get it by the first, and even more by the second. Lots of us new FO's are coming from CFI backgrounds having only flown Cessnas and Seminoles. Its a steep learning curve, and I wish the training department was more sympathetic to that.