Pardon me for chiming in... I've been following this thread with interest, as we are also headed for South Africa this summer.
Lots of useful tips here and my thanks to all for sharing them.
We will be spending almost all of our time at game preserves so I was especially interested in the parts about immunizations. We are planning on taking Malarone and I appreciate the additional info about it. We were advised to get the same shots as SkyCougar listed and, like her, I was surprised to see polio included. We also did not get anything for yellow fever.
We have spread our shot schedule out over a six month period so as to minimize the sore arm effect. Plus we opted for the oral typhoid vaccine.
I have never been a particularly willing recipient of immunizations and, after we are all done, this will be my shot of preference:
Cheers!
Bob